lasmiditan, pentobarbital. Both boosts effects of the other by sedation. Use Caution/Watch. Coadministration of lasmiditan and other CNS depressant medicines, together with Alcoholic beverages have not been evaluated in clinical reports. Lasmiditan may perhaps cause sedation, and also other cognitive and/or neuropsychiatric adverse reactions.

pentobarbital will lessen the extent or effect of larotrectinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the extent or outcome of phenytoin by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Check.

pentobarbital will lessen the extent or impact of eletriptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Caution when discontinuing CYP3A4 inducers that are coadministered with hydrocodone; plasma concentrations of hydrocodone may well improve and may lead to possibly deadly respiratory despair

pentobarbital will decrease the level or effect of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.

pentobarbital will lower the level or influence of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Influence of coadministering a powerful CYP3A4 inducer with fedratinib has not been analyzed.

Info are now not available to Assess influence of barbiturates when forceps supply or other intervention is necessary; also, info are usually not readily available to ascertain the influence 戊巴比妥鈉製作 of such barbiturates over the later progress, advancement, and purposeful maturation of the kid

Contraindicated (one)pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Potent CYP3A4 inducers can lower panobinostat stages by ~70% and result in treatment failure.

With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.

pentobarbital will minimize the level or effect of paclitaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.

pentobarbital will minimize the level or outcome of tamoxifen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lower the extent or effect of nicardipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

sodium oxybate and pentobarbital both enhance sedation. Avoid or Use Alternate Drug. Restrict use to people for whom different therapy choices are insufficient